KRT14

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KRT14

A gene on chromosome 17q12-q21 that encodes a type-I intermediate filament keratin, which typically forms a heterotetramer with KRT5 (type-II) keratins that together form the cytoskeleton of epithelial cells.

Molecular pathology
KRT14 mutations are associated with epidermolysis bullosa simplex.
References in periodicals archive ?
However, with regards to terminal differentiation, there was a remarkable difference in favour of the organ-specific BSCs equivalents, which showed minimal expression of CK14 and obvious expression of CK20, while DF-SMCs equivalents revealed remarkable expression of CK14, mainly in the basal cells with no expression of CK20.
Contract awarded for Supply and installation workmanship that includes diagnosis of operation, technical report and replace the following parts: steam manifold assy, exhaust manifold assy, repair kit Manifold water, repair kit steam trap, cable door solenoid wiring, check valve (ck1, ck2), CK14 check valve, regulating full steam, temperature sensor, heat exchanger, filter air check valve 1/2 "air pressure switch ps1, packaging Door 16" x 16 ", cable assy j11, j12 Cable assy, I / or bord (electronic card), these parts will be replaced car key which its location is the sterilization room hoapital dr raul mena davila brand:.
Immunohistochemically, the neoplastic cells were positive for cytokeratin AE1 / AE3, CK14, smooth-muscle actin, widespread vimentin, focal S-100 protein, focal glial fibrillary acidic protein, and focal epithelial membrane antigen.
9) Cytokeratin 14 (CK14) and cytokeratin 17 (CK17) have both been reported as positive immunostains for BCC, (10) although CK14 has not been studied in BCCm.
Briefly, the tissue was homogenized in 1 mL DNAzol using Precellys 24 bead mill (Bertin, Montigny-le-Bretonneux, France), using ceramic CK14 beads at 5,000g for 10 sec.
There was no staining for AE1 AE3, pancytokeratin, H-caldesmon, myogenin, CK 5/6, CK14, p63, 34BE12, CD34, CK7, CD56, EMA, S100, melan A, c-KIT and CD99.
Yanagita et al (52) created an immunostaining method using a 4-antibody cocktail of TTF-1, napsin A, p63, and CK14 with high specificity and sensitivity for differentiating ACAs and SCCs of the lung.
The monoclonal antibody 34[beta]12 targets cytoplasmic highmolecular-weight cytokeratin filaments in basal cells of the benign prostatic glands, namely CK1, CK5, CK10, and CK14.
Antibodies to uroplakin III (UROIII), S100P, and GATA-3 have been shown to be urothelial-associated markers, while expression of CK14 and desmoglein-3 has been associated with squamous differentiation.
The basal cytokeratin stains (CK5, CK14, and CK17), recently shown to be expressed in the basal phenotype of breast carcinoma, were not present in most other types of PBC.
Antibodies to a number of basal-type and highmolecular-weight cytokeratins, including cytokeratin (CK) 1, CK5, CK5/6, CK10, CK14, and CK17, react variably with breast MECs.