KRT13

(redirected from CK13)

KRT13

A gene on chromosome 17q12-q21.2 that encodes a type-I intermediate filament keratin, which is expressed in corneal epithelia. KRT13 is paired with KRT4 and expressed in the suprabasal layers of non-cornified stratified epithelia.

Molecular pathology
KRT13 mutations are associated with autosomal dominant white sponge nevus.
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Cytokeratin (CK) Expression in Various Carcinoma Types of the Sinonasal Tract and Nasopharynx (a) AE1/AE3 CK5/6 CK7 CK8 CK13 SCC + + (9/10) + (6/10) + (9/10) + (9/10) NKSCC + + (9/10) - + (9/10) + (9/10) SNUC + - + (3/6) + (6/6) - NPC + + (4/5) - + (4/5) + (4/5) CK14 CK19 SCC + (8/10) + (9/10) NKSCC + (8/10) + (9/10) SNUC - + (3/6) NPC - + (5/5) Abbreviations: NKSCC, nonkeratinizing squamous cell carcinoma; NPC, nasopharyngeal carcinoma, undifferentiated type; SCC, squamous cell carcinoma; SNUC, sinonasal undifferentiated carcinoma.
The second group expressed CK13 and CK14 but not the other antibodies studied.