KRT7

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KRT7

A gene on chromosome 12q13.13 that encodes a type-II cytokeratin specifically expressed in the simple epithelia of internal organs, glands, ducts and blood vessels.
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Damavandy's retrospective review of 49 cases may seem small, he said, but it is "far and away the biggest cohort that exists, and the only substantial cohort with immunohistochemistry staining of CK-7.
Immunohistochemistry staining with CK-7 allows highly accurate visualization of individual Paget tumor cells, which express a very high level of the protein.
All were treated with Mohs microsurgery enhanced by CK-7 staining of frozen sections.