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PRNPA gene on chromosome 20p13 that encodes a membrane glycosyl-phosphatidylinositol-anchored glycoprotein, which aggregates into rod-like structures and contains a highly unstable region of five tandem octapeptide repeats. The exact function of PrP is unknown.
PRNP mutations are linked to Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington-like disease 1 and kuru.
CJDCreutzfeldt-Jakob disease, see there.
Patient discussion about CJD
Q. Recently i heard about Creutzfeldt-Jakob disease Recently i heard about Creutzfeldt-Jakob disease. I like to know (To ask the Secretary of State for Health), how many people under the age of 20 years in each of the last five years have suffered from Creutzfeldt-Jakob disease; and of these how many had not had any growth treatment previously? How serious is it?
but it's very elaborated and might give you a clue..