CALCA

(redirected from CGRP1)

CALCA

A gene on chromosome 11p15.2 that encodes peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin, by tissue-specific alternative RNA splicing of gene transcripts and cleavage of inactive precursor peptides. Calcitonin regulates calcium and phosphorus metabolism; calcitonin gene-related peptide is a vasodilator; katacalcin is a calcium-lowering peptide.
References in periodicals archive ?
Through binding to the CGRP1 receptor, ADM further elevates cAMP levels in vascular smooth muscle cells and expands blood vessel diameter.
Calcitonin gene-related peptide-induced suppression of atrial natriuretic peptide release through receptors for CGRP1 but not for calcitonin and amylin.