Avellino corneal dystrophy

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Avellino corneal dystrophy

An autosomal dominant (OMIM:607541) form of corneal dystrophy that is considered a variant of granular dystrophy and has a significant amyloidogenic tendency.

Molecular pathology
Linked to defects of TGFBI, which encodes an RGD protein that binds to type-I, -II and -IV collagens and plays a role in cell–collagen interactions.
References in periodicals archive ?
After the training, average absolute error achieved from the 4 networks; named as QP1 and QP2 for the 2 networks trained in QP and as CGD1 and CGD2 for the networks trained in CGD; are 0.
77 Error(Testing) Network Name CGD1 CGD2 NETWORK TOPOLOGY Network type feed-forward feed-forward fully connected fully connected network network Number of inputs 1 1 Number of hidden 2 2 layers Hidden units in the 6 6 1st hidden layer Hidden units in the 8 8 2nd hidden layer Number of outputs 1 1 All the topology are created using genetic algorithms with following parameters Population size 40 40 Number of 60 60 generations Network size penalty 5 5 Crossover rate 0.