CES3

CES3

A gene on chromosome 16q22.1 that encodes a carboxylesterase which plays a role in detoxifying xenobiotics (e.g., cocaine and heroin) and in activating ester and amide prodrugs. It is primarily expressed in the intestine and liver.
References in periodicals archive ?
Professor of engineering at Cambridge University and chairman of Granta Design Limited, Michael Ashby, says CES3 arms the engineer with the full set of information and analysis to help them make the best possible design decisions.
Enzyme Preparation used Substrate sEH Recombinant purified enzyme CMNPC CES1 Recombinant partially purified enzyme CMNA CES2 Recombinant partially purified enzyme CMNA CES3 Recombinant partially purified enzyme CMNA FAAH Recombinant microsomes Octanoyl-MP PON2 Recombinant microsomes CMNA GSTs Pooled human liver cytosol CDNB CYP450 1A2 and 2C6 Pooled human liver microsomes EROD CYP450 2C9 Pooled human liver microsomes Luciferin H Enzyme Concentration Buffer ([mu]/M) sEH 5 Bis-Tris/HCI pH 7.
50] (nM) (a) sEH Siduron 33 [+ or -] 3 TCC 13 [+ or -] 1 CES1 Triclosan 210 [+ or -] 20 TPP 43 [+ or -] 3 CES2 Carbophenothion 34 [+ or -] 1 Triclosan 580 [+ or -] 30 TPP 50 [+ or -] 2 CES3 Carbophenothion 110 [+ or -] 15 Parathion 4 9 [+ or -] 0.
PTM also revealed several genes, including C-CAM4, CAP2, SERPIN7A, CES3, and expressed sequence tags (ESTs) not yet associated with the AhR signaling pathway (Table 3).
Recognized dystocia scores were CES1 = no problem, CES2 = slight problem, CES3 = needed assistance, CES4 = considerable force, CES5 = extreme difficulty.