CDw75

CDw75

a type II transmembrane protein present on mature B cells and some T cells that may facilitate B-cell adhesion; expressed in B-cell lymphomas of follicular cell origin.
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Markers that were negative (0%) included CD30 (n = 6), [kappa] light chain (n = 2), [lambda] light chain (n = 2), CD8 (n = 2), CD1a (n = 1), CD2 (n = 1), CD5 (n = 1), CD7 (n = 1), CD15 (n = 1), CD45RO (n = 1), CDw75 (n = 1), CD79a (n = 1), CD123 (n = 1), CD138 (n = 1), PAX5 (n = 1), TCL-1 (n = 1), and anaplastic lymphoma kinase (ALK; n = 1).
Unmasking antigen retrieval was used with the CD3, CD5, CD10, CD20, CD23, and CDw75 immunoperoxidase stains.
1,2,8] Immunophenotypically, the neoplastic B cells stain uniformly positive for most B-cell markers, such as CD20, CD45RA, CD79a, MB1, MB2, CDw75, and CD74, but they are negative for T-cell markers, myelomonocytic marker CD15, and activating marker CD30.