CDK8


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CDK8

A gene on chromosome 13q12 that encodes a cyclin-dependent kinase, which regulates cell cycle progression. CDK8 and its regulatory subunit, cyclin C, belong to the RNA polymerase II holoenzyme complex.
References in periodicals archive ?
Through further functional studies, researchers found that eliminating macroH2A led to an increase in CDK8 expression, and the elimination of CDK8 in metastatic melanoma cells impaired their proliferation.
Scientists think the gene CDK8 plays a role in many varieties of colon cancer.
The gene - called CDK8 - was found to be prevalent among colon cancer victims after scientists scanned tumour cells for genes that drive the spread of colon cancer cells and therefore tumours.