CDH3

CDH3

A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH3 is also a retired HUGO symbol for what is now designated CDH15, see there.

Molecular pathology
Loss of heterozygosity mutations of CDH3 occur in breast and prostate cancer; aberrant expression of cadherin 3 occurs in cervical adenocarcinomas. CDH3 mutation causes congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia with ectrodactyly and macular dystrophy.
References in periodicals archive ?
Mellanox has been certified on all previous versions of Cloudera solutions, including CDH3 and CDH4, so customers can securely deploy their choice of data intensive applications delivering performance, resiliency and cost effectiveness, using Mellanox interconnect solutions.
Revolution Analytics has increased support for Hadoop as a platform for Big Data analytics with Cloudera CDH3 and CDH4 in its upcoming release of Revolution R Enterprise 7.
2, currently available, is certified to work with Cloudera CDH3 and CDH4, allowing researchers to write their own Hadoop-based analytics in R and deploy them within the Cloudera environment.
The company has invested tremendous support for the Hadoop ecosystem and has already integrated Revolution R Enterprise with Cloudera CDH3 and CDH4, and IBM BigInsights version 2.
74) Eleven genes--COL1A2, COL6A1 (collagen), tPA, MMP9 (protease), CDH3, L1CAM, ITGB4, PLXNA3/PLXN3, KRT14/K14 (cell adhesion or cell surface molecule), SEMA3C (semaphorin), and CXCL10/INP10 (chemokine)--were overexpressed in MPM.
In the comparative study with normal cells quoted above, (74) SEMA3C, ITGB4, CDH3, and COL6A1 were highly expressed in the epithelioid MPM subtype; L1CAM, K14, and INP10 were overexpressed in the mixed MPM subtype; and MMP9 and PLXN3 were overexpressed in the sarcomatoid MPM subtype.
Four genes namely LAMB1, CDH1, CDH3 and HNF4A play vital roles in keeping the intestine lining healthy.
Tags: Big Data, Apache Hadoop, Big Data Analytics, Cloudera CDH3
Results achieved in September, 2011 show that a 20-node SGI Hadoop cluster comprised of SGI[R] Rackable[TM] C2005-TY6 half-depth servers with Intel[R] Xeon[R] processor E5630 series, 48GB of memory, and 4x 1TB SATA HDDs running on Cloudera CDH3 took only 130 seconds to complete a Terasort with a job size of 100GB.
Karmasphere[TM], a Big Data Analytics company, today announced support for Cloudera CDH3 Beta 4, the latest version of the Hadoop Big Data platform from the provider of Apache Hadoop-based data management software and services.
Synthesys is one of the first products to fully leverage the latest version of these technologies - Hadoop CDH3 and Cassandra v0.