LMNA

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LMNA

A gene on chromosome 1q22 that encodes lamin A/C, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.

Molecular pathology
LMNA mutations cause the so-called laminopathies—e.g., Charcot-Marie-Tooth disease type 2B1, progeria (Hutchinson-Gilford syndrome), dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy type 2, familial partial lipodystrophy, limb-girdle muscular dystrophy type 1B, mandibuloacral dysplasia, and some cases of Werner syndrome.
References in periodicals archive ?
Having reviewed the market, CDDC opted to implement CommuniGate Pro http://www.
lt]) data show statistically significant reductions in strength values of FRP treated with CDDC (27% reduction) and the high concentration of CCA (25% reduction) when compared to other treatments and the untreated controls (Tables 4 and 5).
STARTING POINT: James Gill, left, of NRG and John Hildreth, CDDC business development executive, launch the new NETPark Affinity programme.
RiverSouth is a great success story for the residents of Columbus," said Guy Worley, CEO of CDDC.
com/spacetech or call CDDC on 0191 370 8680 for more information.
Stewart Watkins, managing director of CDDC, said: "Kromek's growth at NETPark is proof not only of the strength of its products, but also of the potential NETPark has as a place where science and technology companies can access the right support and facilities to blossom.
Stewart Watkins, managing director of CDDC, said: "Dr Buckley and his team have gained a reputation for excellence within the photovoltaic field and we're delighted that he'll be giving a real insight into the industry at Solar Flair.
Stewart Watkins, managing director of CDDC, which manages NETPark, said the new facility would take the business park "to the next level".
Stewart Watkins, managing director of CDDC, said: "This year we've attracted some of the biggest names in the photovoltaic industry and their insight into the solar power revolution will be invaluable for businesses looking to develop in this cutting edge field or gain insider tips to expand their companies further.
Mellon Foundation supported the development of BiblioVault and the CDDC with three grants totaling $3.