CDC20

(redirected from CDC20 cell division cycle 20 homolog)

CDC20

A gene on chromosome 1p34.1 that encodes a regulatory protein which interacts with other proteins at multiple points in the cell cycle. CDC20 is required for two microtubule-dependent processes: nuclear movement prior to anaphase and chromosome separation. CDC20 is required for full ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. It is regulated by MAD2L1.
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8] Human genes: ARHGDIB, Rho GDP dissociation inhibitor (GDI) [beta]; BCL2, B-cell CLL/lymphoma 2 (transcript variant [alpha]); CDC20, CDC20 cell division cycle 20 homolog (S.