CDC20

CDC20

A gene on chromosome 1p34.1 that encodes a regulatory protein which interacts with other proteins at multiple points in the cell cycle. CDC20 is required for two microtubule-dependent processes: nuclear movement prior to anaphase and chromosome separation. CDC20 is required for full ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. It is regulated by MAD2L1.
Mentioned in ?
References in periodicals archive ?
Also DNA damage response may play a positive role in repair damaged DNA of early embryos, and it may benefit from the functions of [gamma]H2AX below: firstly, [gamma]H2AX may work as it collects other signal or repair proteins to injured sites [16, 17, 23]; secondly, it localizes at kinetochores and calls together MDC1, MDC2, and CDC20 for assembling an integrated mitotic checkpoint complexes [34]; finally, dynamic [gamma]H2AX in cell cycle reminds us of its specific role in the process of mitosis [18,35].
THE ROLE OF DIA2 AND CDC20 IN UV-ACTIVATED REPAIR PATHWAYS
9:20 THE ROLES OF CDC20 AND RAD4 IN DOUBLE STRAND BREAK
CDC20 and cyclinA2 are both involved in the cell's progression from metaphase to anaphase, with CDC20 being necessary to activate the anaphase promoting complex leading to the degradation of cyclinA2 (Dunican et al.
Reintroduction of RAD4 or CDC20 under the control of a galactose inducible promoter gal1 into [DELTA]rad4 and [DELTA]rad4/cdc20-1 strains returned moderate UV sensitivity to both.
6] ACTB molecules included MMP16, TPBG, LGALS9, CDC20, RAG1, and IFNG.
For CDC20, FANCG, IFNG, and TPNG the visit-to-visit variance component was somewhat higher, 5%-10%.
8] Human genes: ARHGDIB, Rho GDP dissociation inhibitor (GDI) [beta]; BCL2, B-cell CLL/lymphoma 2 (transcript variant [alpha]); CDC20, CDC20 cell division cycle 20 homolog (S.
10:45 CDC20 LINKS NUCLEOTIDE EXCISION REPAIR TO CELL CYCLE PROGRESSION