The aim of this study was to determine the significance of flow cytometry and CD87, CD45 and CD56 expressions in the diagnosis, follow-up and prognosis of multiple myeloma (MM).
A panel of CD87, CD45, CD56, CD 10, CD19, CD20, CD38, and CD138 was tested by flow cytometry.
Further clinical studies including large numbers of patients are needed to determine the prognostic role of CD87 in MM.
Key words: Multiple myeloma, uPA, CD87 (uPAR), flow cytometry
Bu calismada MM tani, takip ve prognozunda alim sitometri metodunun ye CD87, CD45, CD56 ekspresyonunun onemini belirlemek amaclanmistir.
Hastalara akim sitometri yontemi ile CD87, CD45, CD56, CD10, CD19, CD20, CD38, CD138'i iceren panel calisildi.
MM'da CD87 ekspresyonunun prognostik rolunu belirlemek icin cok sayida pasta iceren daha fazla klinik calismaya ihtiyac vardir.
Anahtar kelimeler: Multipl miyelom, uPA, CD87 (uPAR), akim sitometri
CD87 has a number of regulatory effects on cell migration, leukocyte adhesion, chemotaxis, and signal transduction.
Therefore, CD87 expression was evaluated with CD56 and CD45 in our study.
In this study, we examined the frequency of CD87, CD45, and CD56 expressions and their association with other prognostic parameters such as age, (32-m and albumin levels, genetic abnormalities, and disease stage and subtype.