CD83

CD83

a type I transmembrane protein, present on dendritic cells, Langerhans cells, B cells, and interdigitating reticular cells; may play a role in antigen presentation or the cellular interactions that follow lymphocyte activation.
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Ademas, pueden favorecer la maduracion de las celulas dendriticas (DC, por su sigla en ingles) mediante la produccion de citocinas, incluyendo IL-12p70, asi como el aumento en la expresion de CD80, CD83, CD86 y CMH-II (23).
2] qPCR Primer Assay for human CD83 and as housekeeping genes [RT.
27-Hydroxycholesterol (27OHChol) also rapidly induces the differentiation of THP1 cells into mDCs [14] with high expression of mDC-specific markers such as CD80, CD83, CD86, and CD88.
Morphological changes and the upregulation of costimulatory molecules (CD86, CD83, CD80, and CD40) during DC maturation are essential for the activation and recruitment of T cells or other immune effectors.
Transcription analysis of 44 CD genes was also carried out, indicating 24 CD genes (CD3E, CD244, CD69, CD247, CD40L, CD38, CD5L, CD44, CD5, CD83, CD163L1, CD36, CD14, CD28, CD200R1A, CD40, CD59, CD200, CD4, CD2, CD72, CD180, CD79B, and CD93) to be markedly increased by 2.
Alcohol also suppressed expression of the co-stimulatory molecule CD83 during DC maturation, which may attenuate the ability of DCs to initiate T-cell expansion (Siggins et al.
DC-SIGN-positive cells appear to be immature dendritic cells in that they did not express the dendritic cell maturation molecule CD83.
To assess the maturation status of lung CD11c+CD14-mDCs after IAV infection, the co-stimulatory markers such as HLA-DR, CD80, CD83, and CD86 were analyzed by FACS.
Expression of the CD83 transmembrane domain in DCs interferes with modulation of MHC II and B7.
However, no significant difference was observed in cell proliferation, morphology and phenotype between group A and B, but the mRNA expression levels of surface marker genes, MHC-II, CD40, CD80, CD83 and CD86 were up regulated (<0.
Expression of CCR6 and CD83 by cytokine-activated human neutrophils.