CD8 cells


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Related to CD8 cells: T cells, CD8 alpha, CD4 cells

CD8 cells

T cells with CD8 on the surface, which are immunosuppressive and suppress mitogen-induced and antigen-specific antibody production, and require CD4 cell cooperation
References in periodicals archive ?
TAT2 (GRN 163L), a small-molecule telomerase activator, "modestly" retarded telomere shortening while enhancing antiviral activity of CD8 cells collected from people with HIV.
The researchers speculated that the observed CD8 turnover may result from the CD8 cells exhausting themselves in the face of the AIDS virus, then vigorously renewing their ranks, in an effort to make up for the diminishing ranks of their disease-fighting partners, the CD4 cells.
That's the indirect measure--it's not the CD4 cell that's directly impacting viral load, it's the CD8 cell.
In the body, CD8 cells can transform themselves into killers that seek out and destroy other cells infected by HIV.
Gallo and his coworkers modified CD8 cells to reproduce indefinitely.
This indicates that Multikine treatment shifts the immune response from a mainly CD8 cell anti-tumor response to a predominately CD4 anti-tumor response.
Further studies indicated that the CD8 cells showing antiviral activity secreted the substance researchers named CAF.
The Stanford team found similar numbers of CD8 cells in the two groups.
We will focus on diseases where the immunopathology is mediated by CD4 cells rather than CD8 cells, which are known to be dependent for their activation on the pathway being blocked by IDEC-114," added Dr.
The data show that the vaccine initiates the response through CD8 cells, but CD4 cells and interferon gamma play a more important role in delivering the actual protection to virus challenge.
Normally, these CD8 cells kill other cells and make interferon gamma, a TH1 messenger.
CXCL16 was also detected in some non-lymphoid tissues, including small intestine, lungs, liver and kidney, and in these sites it may help the activated CD8 cells carry out their killer function during infections.