cytotoxic T cell

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Related to CD8 T cells: CD4 T cells, Cytotoxic T lymphocytes

cytotoxic T cell

cytotoxic T cell

See CD8 cell.

cytotoxic T cell

A CD8+ T lymphocyte that can destroy microorganisms directly through the release of perforin and proteolytic enzymes. These cells are particularly important in the defense against viruses, rejection of allografts, and, possibly, new malignant cells. Synonym: CD8 cell; cytotoxic cel; killer T cell
See also: cell
References in periodicals archive ?
Lalvani asserted that their findings suggest that by making the body produce more of this specific type of CD8 T cell, you can protect people against symptomatic illness and this could provide the blueprint for developing a universal flu vaccine.
We already know how to stimulate the immune system to make CD8 T cells by vaccination.
HIV-1 prognosis has been linked to the frequency of CD8 T cells co-expressing CD38 and HLA-DR; and with the positive cut-off of both activation antigens defined by negative isotype control antibodies [7,10,18,69].
Subjects taking Echinacea showed increases in CD4 T cells, CD8 T cells and NK cells.
Indeed, a consensus is that if the immune system is still fairly intact, therapy interruption might indeed boost CD8 T cell responses, which likely contain HIV longer.
The interim results, Recombinant Human Interleukin-7 (CYT107) Enhances CD4 and CD8 T Cell Recovery Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplant In Patients with Myeloid Malignancies (Abstract 674), were presented by Dr.
CD38 expression on CD8 T cells with or without other markers (HLA DR and CD45RA) is not adequate to predict the virological response to antiretroviral therapy (ART) in Ugandans: XVI International AIDS Conference Toronto (Abstr.
Other immune cells eventually suppress CD8 T cells, so the treatment isn't expected to continue to attack healthy melanocytes and, in that way, cause autoimmune disease.
A 5-mg dose that uses the CRL 1005 adjuvant consistently showed the best results, with CD8 T cell responses in particular, in rhesus monkeys immunized at 0, 4, and 8 weeks.
They found that the number of CD8 T cells was similar in progressors and nonprogressors.
Study indicates rhIL-7 blocks sepsis-induced depletion of CD4 and CD8 T cells, enhances lymphocyte recruitment and prevents sepsis-induced loss in immunity leading to improved survival
The instructor cells instruct CD8 T cells to become killer T cells to kill infected cells or cancer cells - and to remain vigilant if they reencounter pathogens or if the cancer comes back.