CD8 cell

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Related to CD8+ cell: Cytotoxic T lymphocytes

CD8 cell

a T lymphocyte that secretes large amounts of gamma-interferon, a lymphokine involved in the body's defense against viruses. CD8 cells prevent the unnecessary formation of antibodies. Also called cytotoxic T cell. See also CD4.

CD8 cell, CD8+ cell

a major classification of T lymphocytes, referring to those that carry the CD8 antigen; the major subtypes are the cytotoxic T lymphocytes and the suppressor cells. Also called CD8 T lymphocytes.

CD8 cell

A suppressor T cell, e.g., a cytotoxic T cell.
See also: cell
References in periodicals archive ?
The antiviral capacity of these virus-specific CD8+ cells is strongly dependent on their ability to migrate and localize to the lungs and infected airway epithelium (14), where they appear 5-7 days after infection (15).
Using the statistical analysis of Lehmacher (SAL), however, a significant difference after 1 week of treatment was found in the number of CD8+ cells (p<0.
Effros and colleagues demonstrated that introducing the telomerase gene into CD8+ cells from HIV/AIDS donors increased their proliferative capacity, their ability to produce IFN(gamma), and their ability to inhibit viral replication and kill HIV-infected T-cells.
Their teams determine relevant antigens within infected cells, which subsequently will be used to identify characteristic parts of these proteins (epitopes) that are required by the CD8+ cells to activate the immune response against these bacteria.
The data also suggests an increase in CD8+ cells in the Ampligen group suggesting an induction of immune cells that have potential to seek and may destroy cells infected with HIV.
Changes in CD4+ cells, CD8+ cells and body weight were monitored at each patient visit.
The TCell-DLI Cell Separation System is an ex-vivo system for removal of CD8+ cells from donor leukocyte infusions.
There are also a number of Isolex(R) systems currently in use in investigational protocols for gene therapy and dendritic cell therapy, engineered transplants with alternative donors and for autoimmune diseases, and depletion of specific T-cell subsets such as CD4+ or CD8+ cells.
In order to evaluate if CD8+ cells were responsible for the increased protection, SCID mice were reconstituted with cells after depletion of CD8+ cells, either from a normal donor or an HGP-30 vaccinee.