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CD8

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CD8 (sd-t)
n.
A glycoprotein on the surface of killer cells that enhances binding with major histocompatibility complex molecules.

CD2
cluster of differentiation or cell differentiation glycoproteins.

CD antigen
a group of cell surface molecules which act as markers on T lymphocytes.
CD3
found on T helper (Th) and T cytotoxic (Tc) lymphocytes; associated with signal transduction.
CD4
found on T helper lymphocytes; an adhesion molecule that binds to class II MHC molecules.
CD8
found on T cytotoxic and variably on NK lymphocytes; an adhesion molecule that binds to class I MHC molecules.

CD8
T8 antigen A disulfide-linked heterodimeric protein, for which each monomer is 32–34 kD; CD8 is a marker for T cells with suppressor and cytotoxic activity; it is a co-receptor with class I MHC antigens on antigen-presenting cells, and is physically associated with a p56 tyrosine kinase, which phosphorylates adjacent proteins; NK cells may weakly express CD8. See Cytotoxic T cells.


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When injected into mice and guinea pigs, dl5-29 survives long enough to infect cells and trigger an immune response that includes antibodies and immune cells called CD8 T cells.
These new assays were based on measuring antigen-specific cytokine production in both CD4 and CD8 T cells from HIV-infected people.
The researchers arrived at their conclusions by measuring certain components of CD4 cells and other immune-system cells known as CD8 cells.
 
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