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a type I transmembrane protein found on suppressor (cytotoxic) T cells, some natural killer cells, and most thymocytes that is involved in T-cell antigen recognition; expressed in some T-cell lymphomas and large granular lymphocyte leukemias.
A glycoprotein on the surface of killer cells that enhances binding with MHC molecules.
CD8T8 antigen A disulfide-linked heterodimeric protein, for which each monomer is 32–34 kD; CD8 is a marker for T cells with suppressor and cytotoxic activity; it is a co-receptor with class I MHC antigens on antigen-presenting cells, and is physically associated with a p56 tyrosine kinase, which phosphorylates adjacent proteins; NK cells may weakly express CD8. See Cytotoxic T cells.
cluster of differentiation or cell differentiation glycoproteins.
a group of cell surface molecules which act as markers on T lymphocytes.
found on T helper (Th) and T cytotoxic (Tc) lymphocytes; associated with signal transduction.
found on T helper lymphocytes; an adhesion molecule that binds to class II MHC molecules.
found on T cytotoxic and variably on NK lymphocytes; an adhesion molecule that binds to class I MHC molecules.