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CD8

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CD8 (sd-t)
n.
A glycoprotein on the surface of killer cells that enhances binding with major histocompatibility complex molecules.

CD2
cluster of differentiation or cell differentiation glycoproteins.

CD antigen
a group of cell surface molecules which act as markers on T lymphocytes.
CD3
found on T helper (Th) and T cytotoxic (Tc) lymphocytes; associated with signal transduction.
CD4
found on T helper lymphocytes; an adhesion molecule that binds to class II MHC molecules.
CD8
found on T cytotoxic and variably on NK lymphocytes; an adhesion molecule that binds to class I MHC molecules.

CD8
T8 antigen A disulfide-linked heterodimeric protein, for which each monomer is 32–34 kD; CD8 is a marker for T cells with suppressor and cytotoxic activity; it is a co-receptor with class I MHC antigens on antigen-presenting cells, and is physically associated with a p56 tyrosine kinase, which phosphorylates adjacent proteins; NK cells may weakly express CD8. See Cytotoxic T cells.


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The team then linked interferon alpha to the activation of one of the heavy artillery of the immune system -- CD8 cells.
The study showed that rapamycin, given to transplant patients to suppress their immune system, can trigger the formation of memory CD8 T cells, enabling the immune system to respond faster upon secondary encounter.
The easy-to-read CD4 assay includes absolute counts and percent positive ratios on the cellular populations of CD3, CD4, and CD8 T-lymphocytes.
 
 
 
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