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CD8 |
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CD2 cluster of differentiation or cell differentiation glycoproteins. CD antigen a group of cell surface molecules which act as markers on T lymphocytes. CD3 found on T helper (Th) and T cytotoxic (Tc) lymphocytes; associated with signal transduction. CD4 found on T helper lymphocytes; an adhesion molecule that binds to class II MHC molecules. CD8 found on T cytotoxic and variably on NK lymphocytes; an adhesion molecule that binds to class I MHC molecules. CD8 T8 antigen A disulfide-linked heterodimeric protein, for which each monomer is 32–34 kD; CD8 is a marker for T cells with suppressor and cytotoxic activity; it is a co-receptor with class I MHC antigens on antigen-presenting cells,
and is physically associated with a p56 tyrosine kinase, which phosphorylates adjacent proteins; NK cells may weakly express CD8. See Cytotoxic T cells. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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When injected into mice and guinea pigs, dl5-29 survives long enough to infect cells and trigger an immune response that includes antibodies and immune cells called CD8 T cells. These new assays were based on measuring antigen-specific cytokine production in both CD4 and CD8 T cells from HIV-infected people. The researchers arrived at their conclusions by measuring certain components of CD4 cells and other immune-system cells known as CD8 cells. |
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