CD69


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Related to CD69: CD25, CD44

CD69

a type II transmembrane protein present on platelets, CD4-positive or CD8-positive thymocytes, activated lymphocytes, and activated T or natural killer cells that functions as a signal transducer, enhancing cell activation and/or platelet aggregation.

CD69

A gene on chromosome 12p13 that encodes a member of the calcium-dependent lectin superfamily of type-II transmembrane receptors, the expression of which is induced by T-cell activation. CD69 is involved in lymphocyte proliferation and acts as a signal-transmitting receptor in lymphocytes, natural killer (NK) cells and platelets.
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10,12), this assay detects the activation marker CD69 on the surface of CD3+ T cells, correlates well with skin test reactivity, and indicates previous (or current) exposure to Coccidioides spp.
Though the stimuli for the CD69 expression and its role in neutrophil are still unknown, some studies have shown its role in regulating the cytokine production (11).
CD69 expression was increased at 24 hours by all three herbs.
During this process, the human transmembrane C-Type lectin protein CD69 and the IL-2 receptor CD25 are expressed on the surface of activated T-cells (Malek 2008).
mRNA production by T cell-associated genes, including CD3D, CCR3, and CD69, and by NK cell-associated genes (KLRD1, KLRK1, and PRF1) shows similar time courses, with highly significant decreases in mRNA production apparent between the preoperative and postoperative time points in both investigated groups (Table 2).
In order to precisely identify the cell types stimulated by P-Dex, we examined the expression of CD69 and CD86 on the surface of mouse splenocytes (Figure 4).
CD69 expression on activated lymphocyte surfaces was found to have increased significantly on both [CD4.
Developed and tested at the Paul Flechsig Institute of Brain Research at the University of Leipzig in Germany, the LymPro Test diagnoses probable AD by measuring disturbances of intracellular mitogenic signaling and then quantifying, among other cellular relationships, the CD69 presentations on the surface of selective peripheral blood lymphocytes (PBLs) with and without mitogenic stimulation.
4] cells) were stained with monoclonal antibodies against toll-like receptor (TLR)-4, HLA-DR (eBioscience, Vienna, Austria), CD14, CD80, CD86, CD40 (Bio-Rad AbD Serotec, Puchheim, Germany) for DCs and against CD4, CD69, CTLA-4, CD40L (eBioscience) and CD54 (Bio-Rad AbD Serotec) for allogeneic [CD4.
Monocytes in HIV-infected patients frequently express activation markers (CD38, CD69, CD11b, HLA-DR) [48-50] and secrete proinflammatory cytokines (e.
Nickel induces CD69 expression in lymphocyte subpopulations of allergic patients with contact dermatitis (5).