CD66e | definition of CD66e by Medical dictionary
a glycosylphosphatidylinositol-anchored membrane protein present in tissues derived from all three germ layers during embryogenesis and adult colon epithelial cells; facilitates calcium-independent adhesion during embryogenesis; expressed in most colon carcinomas and other carcinomas.
References in periodicals archive
CEA, now also designated according to the international CD coding system as CD66e
, was subsequently purified in our laboratories in conjunction with John Krupey and Chaim Banjo, and a virtually complete structural analysis of this glycophosphatidyl inositol-bound cell surface glycocalyceal glycoprotein followed (35).
CEA, also called CD66e
or CEACAM5, was selected as target antigen for development of a new BiTE antibody program because CEA is widely expressed on the surface of human carcinoma cells.