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CEA, now also designated according to the international CD coding system as CD66e, was subsequently purified in our laboratories in conjunction with John Krupey and Chaim Banjo, and a virtually complete structural analysis of this glycophosphatidyl inositol-bound cell surface glycocalyceal glycoprotein followed (35).
CEA, also called CD66e or CEACAM5, was selected as target antigen for development of a new BiTE antibody program because CEA is widely expressed on the surface of human carcinoma cells.