CD62l


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Related to CD62l: CD69, CD44, CCR7

CD62l

a type I transmembrane protein present on B cells, T cells, neutrophils, thymocytes, monocytes, eosinophils, erythroid and myeloid progenitor cells, and natural killer cells; functions as a peripheral lymph node homing receptor and facilitates binding to endothelium at inflammatory sites; found on many malignant leukocytes.

SELL

A gene on chromosome 1q23-q25 that encodes l-selectin, a cell surface adhesion/homing receptor required for binding and rolling of leukocytes on endothelial cells, facilitating leukocyte migration into secondary lymphoid organs and inflammation sites. 

Molecular pathology
SELL polymorphisms are associated with various diseases, including IgA nephropathy.
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References in periodicals archive ?
Altered expression of CD11b/CD18 and CD62L on human monocytes after cell preparation procedures.
Cloyd of the University of Texas Medical Branch at Galveston and his colleagues showed that when HIV binds to any of several types of immune cells, including CD4, those cells produce higher than normal amounts of a protein known as CD62L and then move directly into the lymph nodes.