CD55

CD55

a glycosylphosphatidylinositol-anchored membrane protein present on all hemopoietic cells and spermatozoa that neutralizes complement activation; absent or defective in paroxysmal nocturnal hemoglobinuria.
References in periodicals archive ?
CD3, CD4, CD9, CD11, CD19, CD20, CD22, CD26, CD27, CD28, CD29, CD33, CD37, CD40, CD44, CD45, CD47, CD52u CD55, CD56, CD66, CD70, CD74, CD80, CD95, CD98, CD100, CD117, CD135, CD137, CD152, CD200, CD223, CD227, CD246, CD248, CD274, CD276, CD279
Trimesurus flavoviridis (habu snake) venom induces human erythrocyte lysis through enzymatic lypolisis, complement activation and decreased membrane expression of CD55 and CD69.
This has been achieved by inserting into the pig genes one or more human complement-regulatory proteins, such as CD55 or CD46 (44, 45).
The disorder causes partial or complete deficiency of the complement inhibitors CD55 and CD59, which results in red blood cell susceptibility to terminal complement-mediated lysis.
105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55.
In an effort to understand the pathogenesis of anaemia in Pf infection we studied the relationship between expression level of CD35, CD55 and CD59 with haemoglobin status in a group of malaria cases from three regions of India, namely Assam, Goa and Chennai.
Deficiencies in red blood cell CR1 and CD55 in children with SMA were accompanied by a marked decline in immune complex binding capacity and increased C3b deposition in vivo and ex vivo.
CGEN-671 is a membrane splice variant of CD55, a known drug target for gastric cancer for which monoclonal antibody (mAb) therapeutics are in clinical development by others.
To explore the economic consequences of introducing the newly developed CD55, we calculated both the intervention costs and the costs of laboratory requests.
The Scottish Executive awarded Viragen's CD55 Project the maximum dollar amount eligible to be granted by its 'SPUR Plus' program," stated Dr.
Characterization of human CD55 and CD59 transgenic pig and kidney xenotransplantation in the pig-to-baboon combination.