Also found in: Acronyms.
In a study of a therapeutic agent, the dose that cures 50% of the test subjects, that is, the mean curative dose.
a type I transmembrane protein present on thymocytes, B cells, monocytes, and neutrophils; involved in intracellular adhesion.
CD50median curative dose.
ICAM3A gene on chromosome 19p13.3-p13.2 that encodes an intercellular adhesion molecule which, like all ICAMs, is a type-I transmembrane glycoprotein with multiple immunoglobulin-like C2-type domains, and which binds to leukocyte adhesion LFA-1 protein. ICAM3 is expressed by all leukocytes and is the most important ligand for LFA-1 in initiating the immune response, participating in adhesion and signalling.
median curative dose.