In contrast, 23 CD genes (CD3E, CD69, CD48
, CD274, CD40L, CD59, CD40, CD93, CD247, CD28, CD5L, CD38, CD44, CD200R1A, CD14, CD5, CD83, CD2, CD200, CD4, CD79B, CD72, and CD180) were significantly increased by 2.
In the comparison of B-CLL and myeloid leukemia, most of the statistically significant probes with higher hybridization signals in B-CLL samples represented B lymphocyte-associated genes, such as BTG1, CD79A, FAIM3, CCR7, CD48, and HLA-DRA (28).
5] Human genes: CD2, CD2 molecule; CD3E, CD3e molecule, e (CD3-TCR complex); LCK, lymphocyte-specific protein tyrosine kinase; GZMA, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); CD28, CD28 molecule; MNDA, myeloid cell nuclear differentiation antigen; LYN, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; MYC, v-myc myelocytomatosis viral oncogene homolog (avian); BTG1, B-cell translocation gene 1, anti-proliferafive; CD79A, CD79a molecule, immunoglobulin-associated a; FAIM3, Fas apoptotic inhibitory molecule 3; CCR7, chemokine (C-C mofif) receptor 7; CD48, CD48 molecule; HLA-DRA, major histocompatibility complex, class II, DR a; FCER2, Fc fragment of IgE, low affinity II, receptor for (CD23); CD52, CD52 molecule.
In the July 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, the researchers identify CD48
, which adorns the surface of mast cells, as the protein that performs that binding.