CD46


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CD46

a type I transmembrane protein present on thymocytes, T cells, B cells, natural killer cells, monocytes, neutrophils, platelets, endothelial cells, epithelial cells, fibroblasts, placenta, and sperm that protects against complement-mediated damage.
References in periodicals archive ?
Part II discusses pathogens, covering gp41 in HIV defense, LC3 in hepatitis infection, unfolded proteins in immune suppression, mycobacteria, parasitic protists, the CD46 receptor, and Helicobacter pylori.
Number of diallelic sites (SNPs) identified for CD46, by population * No.
for the HIV vaccine, the National Institutes of Health (NIH) for the Ebola vaccine and Centocor, a Johnson & Johnson company, for the CD46 antibody for treatment of various types of cancer.
for the HIV vaccine, the National Institutes of Health (NIH) for the Ebola vaccine and Centocor, a Johnson & Johnson company that has taken out a license on the CD46 antibodies, for the treatment of various types of tumors.
An immunohistochemical study of the distribution of the measles virus receptors, CD46 and SLAM, in normal human tissues and subacute sclerosing panencephalitis.
Louis Project title: "Characterization of CD46 Generated T Regulatory Cells" Dr.
A safer option for measles patients, says Griffin, might be to develop a drug that prevents CD46 from telling cells to stop making IL-12.
for the HIV vaccine, the National Institutes of Health (NIH) for the Ebola vaccine and Centocor, a Johnson & Johnson company that has taken out a licence on the CD46 antibodies, for the treatment of various types of tumours.
Transgenic pigs for human complement-regulatory proteins (CRPs) such as human decay-accelerating factor (hDAF), CD46 and CD59 have been characterized (Byrne et al.
Measles viruses on throat swabs from measles patients use signaling lymphocytic activation molecule (CDw150) but not CD46 as a cellular receptor.
In addition, simultaneous expression of multi-genes, such as human complement regulatory protein (hDAF, CD46, CD59), is needed to protect from HAR and AHXR.
This was a logical choice, since PC cells typically overexpress the measles virus receptor CD46.