Changes in initial CD4 cell count
were examined in four separate time periods: 1985-1990; 1991-1995; 1996-2001; and 2002-2007.
The findings, presented last week at the Sixteenth Conference on Retroviruses and Opportunistic Infections in Montreal, are likely to strengthen the case for a stronger global recommendation that people with HIV should start treatment when the CD4 cell count
falls below 350 cells/[mm.
SEATTLE -- Initiating highly active antiretroviral therapy when the patient still has a CD4 cell count
between 351 and 500 cells/ [micro]L may be associated with less mortality than waiting until the CD4 count drops below 350 cells/ [micro]L, as is often the standard practice, Dr.
Median baseline viral load was approximately 40 000 copies/ml and the median CD4 cell count
was 472 cells/ [mm.
Complete CD4 cell count
data for up to 96 weeks following virologic failure was available for 134 patients.
The investigators suggest that better cancer prevention, monitoring and care could help reduce the number of deaths caused by malignancies in patients with HIV, and also stress the importance of keeping the CD4 cell count
of HIV-positive individuals above 250 cells/[mm.
And CD4 cell count
years above 1600 lowered chances of virus-related cancer 70%.
We sought to evaluate whether insurance was a barrier for patients to enter care for HIV infection by comparing the CD4 cell count
levels and HIV viral loads at the time of entry into medical care to three different types of infectious disease practices.
A CD4 cell count
below 500 is considered a sign of a weakened immune system, as it indicates lower numbers of white blood cells that fight infections and inflammation.
Some studies have also shown that people treated with AZT have smaller increases in CD4 cell count
compared with individuals taking alternative NRTIs.
In addition, we excluded patients who did not have current clinical status available, which was assessed using a patient's most recent viral load and CD4 cell count
in the 6 months before the interview date.
Two cases of HSIL+ were observed during the 5 years of observation, 1 among the HIV-uninfected women and 1 among the HIV-infected women with a CD4 cell count
of 500 cells/uL or greater.