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CD4 cell count |
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CD4 cell count, a measure of the number of "helper" T cells that carry the CD4 glycoprotein on their cell surface and that help B cells produce certain antibodies. The human immunodeficiency virus (HIV) binds to CD4 and kills T cells bearing this glycoprotein. Thus, the CD4 cell count is an indicator of the progress of an HIV infection and helps measure the effectiveness of anti-HIV drugs. CD4 T cells mainly produce interleukin 2, an autocrine and paracrine T cell growth factor; preactivated or memory CD4 T cells secrete a much larger array of lymphokines on restimulation. See also CD4, CD8 cell, human immunodeficiency virus, T cell. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Once your body''s CD4 cell count falls below 200 per cubic millimeter of blood, and/or an opportunistic infection takes hold of your weakened immune system, you will be diagnosed with AIDS (Acquired Immunodeficiency Syndrome). Of these, 71% had a CD4 cell count of more than 200 cells/ [mm. National guidelines in both countries have recommended HAART initiation at a CD4 cell count <300 cells/[micro]L, a threshold that has not changed since 1997. |
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