CD4 cell count

CD4 cell count

a measure of the number of "helper" T cells that carry the CD4 glycoprotein on their cell surface and that help B cells produce certain antibodies. The human immunodeficiency virus (HIV) binds to CD4 and kills T cells bearing this glycoprotein. Thus, the CD4 cell count is an indicator of the progress of an HIV infection and helps measure the effectiveness of anti-HIV drugs. CD4 T cells mainly produce interleukin 2, an autocrine and paracrine T cell growth factor; preactivated or memory CD4 T cells secrete a much larger array of lymphokines on restimulation. See also CD4, CD8 cell, human immunodeficiency virus, T cell.
References in periodicals archive ?
HIV-INFECTED INDIVIDUALS who have experienced a nonmelanoma skin cancer may be at significantly greater risk of subsequent new squamous cell carcinoma if they have a lower CD4 cell count, a new study suggests.
The panel concluded that newer data support the "widely accepted" recommendation that antiretroviral therapy (ART) should be started in all individuals with HIV infection with detectable viremia regardless of CD4 cell count.
CD4 cell count was categorized as <50, 50-199, 200-349, and over 350 cells/mm [sup]3 .
And CD4 cell count years above 1600 lowered chances of virus-related cancer 70%.
We sought to evaluate whether insurance was a barrier for patients to enter care for HIV infection by comparing the CD4 cell count levels and HIV viral loads at the time of entry into medical care to three different types of infectious disease practices.
The portable and wirelessly connected diagnostic is able to measure a patient's CD4 cell count within 15 minutes from a single drop of blood.
Fifty nine patients came for the regular clinical follow up every 15 days in ART clinic and were investigated for evaluation of CD4 cell count every six months following HAART commencement.
86%) of them had CD4 cell count [less than or equal to] 200cells/[micro]l and 19 (27.
The goal of anti-retroviral therapy (ART) in HIV is to bring down the viral load and increase the CD4 cell count so that the body reconstitutes its immune system AND increases the CD4 count to a manageable level of 500 and more.
Some studies have also shown that people treated with AZT have smaller increases in CD4 cell count compared with individuals taking alternative NRTIs.
In addition, we excluded patients who did not have current clinical status available, which was assessed using a patient's most recent viral load and CD4 cell count in the 6 months before the interview date.
Two cases of HSIL+ were observed during the 5 years of observation, 1 among the HIV-uninfected women and 1 among the HIV-infected women with a CD4 cell count of 500 cells/uL or greater.