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CD4 cell |
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CD4 cell, CD4+ cell, a major classification of T lymphocytes, referring to those that carry the CD4 antigen; most are helper cells. Also called CD4 T lymphocytes. CD4 cell CD4+ lymphocyte A circulating T cell with a 'helper' phenotype; in AIDS Pts, the levels of CD4+ cells is a crude indicator of immune status and susceptibility to certain AIDS-related conditions; these Pts may suffer KS as
CD4+ cells fall below 0.3 x 109/L–US: 300/mm3, NHL < 0.15 x 109/L–US: 150/mm3, Pneumocystis carinii < 0.1 x 109/L–US: 100/mm3, MAC < 0.05 x 109/L–US: 50/mm3. See CD4 count, Kaposi sarcoma. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Costs among the sickest patients (those with the lowest CD4 cell counts) come to nearly triple those among individuals whose disease is least advanced. Patients must be three-class experienced with at least two PI-based regimens, and have a CD4 cell count of equal or less than 200 cells/mm3. The problem with CD4 cell changes as a surrogate marker was that CD4 cell count was a direct marker of a person's immune status, but only an indirect marker of anti-HIV drug activity (it rose when HIV levels fell). |
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