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CD4 cell

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CD4 cell, CD4+ cell,
a major classification of T lymphocytes, referring to those that carry the CD4 antigen; most are helper cells. Also called CD4 T lymphocytes.

CD4 cell
CD4+ lymphocyte A circulating T cell with a 'helper' phenotype; in AIDS Pts, the levels of CD4+ cells is a crude indicator of immune status and susceptibility to certain AIDS-related conditions; these Pts may suffer KS as CD4+ cells fall below 0.3 x 109/L–US: 300/mm3, NHL < 0.15 x 109/L–US: 150/mm3, Pneumocystis carinii < 0.1 x 109/L–US: 100/mm3, MAC < 0.05 x 109/L–US: 50/mm3. See CD4 count, Kaposi sarcoma.


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Since age exposes cells to increasing levels of stressors such as oxidative damage (aka "free radicals") that promote changes associated with cancer, the authors speculate that the strategy of maintaining CD4 cell numbers by increasing the life spans of individual cells rather than by promoting proliferation of new cells may be a safeguard of sorts against tumor development.
They use human CD4 cells to manufacture new copies of themselves and kill the CD4 cells in the process.
HIV testing and counselling is offered at the first prenatal visit and CD4 cell counts are done for those who test positive.
 
 
 
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