CD4 T cells

CD4 T cells

Helper T cells, see there.
References in periodicals archive ?
Ablation of thymic export causes accelerated decay of naive CD4 T cells in the periphery because of activation by environmental antigen.
Previous study has shown that a specific type of immune cells, called CD4 T cells, which are critical to vaccine response, become less effective with age.
Previous lab tests had suggested that valproic acid could rouse HIV resting in CD4 T cells.
Other researchers showed that HIV grew much better and evolved much faster in HIV-specific CD4 T cells than in other CD4 cells.
When given to chronically HIV-infected patients during an STI, GM-CSF blunted viral rebound and substantially prevented decreases in CD4 T cells in the absence of antiretroviral treatment.
LAUSANNE, Switzerland -- A study published today online in The Journal of Experimental Medicine has identified the population of CD4 T cells serving as the major reservoir for HIV infected cells and as the primary cell site for HIV replication and production in infected patients.
Severe depletion of mucosal CD4 T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys
At about the same time, immune studies showed that HIV-specific CD4 T cells could be found, especially in the newly infected and in those treated early after infection.
Typically, scientists follow immune system decline by measuring the blood concentrations of the specific type of immune cell, called CD4 T cells, that is targeted by HIV.
This study suggests that a new frontier in HIV therapy can be defined by the recovery and maintenance of a high level of CD4 T cells and that IL-7, with its potential ability to significantly impact naive and memory T cell subpopulations, may be a key to restoring the homeostatic equilibrium which is not achieved by the control of viral load alone under HAART.
Patients with greatest benefit are usually those with relatively low tumor burden who are nmve to antiretroviral therapy and KS therapy in whom HIV viral load decreases to undetectable levels and CD4 T cells increase by 150 cells/[mm.
One way HIV attacks the immune cells known as CD4 T cells is by binding to the protein encoded by CCR5.