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CD4 cell
(redirected from CD4+ cell)

   Also found in: Dictionary/thesaurus 0.01 sec.
CD4 cell, CD4+ cell,
a major classification of T lymphocytes, referring to those that carry the CD4 antigen; most are helper cells. Also called CD4 T lymphocytes.

CD4 cell
CD4+ lymphocyte A circulating T cell with a 'helper' phenotype; in AIDS Pts, the levels of CD4+ cells is a crude indicator of immune status and susceptibility to certain AIDS-related conditions; these Pts may suffer KS as CD4+ cells fall below 0.3 x 109/L–US: 300/mm3, NHL < 0.15 x 109/L–US: 150/mm3, Pneumocystis carinii < 0.1 x 109/L–US: 100/mm3, MAC < 0.05 x 109/L–US: 50/mm3. See CD4 count, Kaposi sarcoma.


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However, while characterizing the earliest stages of infection, Haase's team found how and when the immune system recruits more CD4+ cells to the site of infection - a response that helps the virus to spread.
Prolonged use of HAART and higher CD4+ cell counts were both associated with a reduced risk of menstrual problems, due to the women's better overall health.
All HIV models presented thus far have considered the CD4+ cell immune subset as a single entity, and their principal goal has been to model its decline, as well as its viral dynamics.
 
 
 
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