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CD4 |
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CD4 A type of protein molecule in human blood that is present on the surface of 65% of human T cells. CD4 is a receptor for the HIV virus. When the HIV virus infects cells with CD4 surface proteins, it depletes the number of T cells, B cells, natural killer cells, and monocytes in the patient's blood. Most of the damage to an AIDS patient's immune system is done by the virus' destruction of CD4+ lymphocytes. CD4 is sometimes called the T4 antigen. Mentioned in: AIDS, AIDS Tests CD4 (T4) lymphocyte, n an immunologically important white cell that is responsible for cell-mediated immunity. It is the cell invaded by the human immunodeficiency virus and in which the virus replicates itself. |
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| PcP incidence was highest in patients with the lowest CD4 counts, but PcP is uncommon compared with incidences of pulmonary tuberculosis and bacterial pneumonia. Costs among the sickest patients (those with the lowest CD4 cell counts) come to nearly triple those among individuals whose disease is least advanced. For 4 weeks, each patient received twice-daily injections of enfuviritide, which inhibits HIV from invading fresh CD4 T cells--the primary cells that HIV commandeers. |
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