CD3 antigen

CD3 antigen

A cell membrane complex of five polypeptide chains that is the signal transduction element of the T cell receptor on helper and cytotoxic T cells. Transduction occurs on interaction with antigen.
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Other than CD3 antigen, TCAs are infrequently investigated in routine HL cases.
Table 4: Technological characteristics of Mab products in China Non-proprietary Technology source Technological name characteristics Mouse anti-human Self-development A pioneer in the CD3 antigen of T Chinese Mab market; lymphocytes for direct effect on T injection cells that play a major role in organ transplant rejection.
Neoplastic cells of the penguin as well as of the pelican were immunoreactive to CD3 antigen, suggesting the lymphomas were of T-cell origin.
T-cell lymphoma, CD3 antigen, avian, melanoma, penguin, Spheniscus humboldti, pelican, Pelecanus rufescens
The T-cell origin was proven immunohistochemically by positive reaction to CD3 antigen.
The CD3 antigen consists of at least 5 invariable/constant membrane proteins and is associated with 2 variable immunoglobulin-like glycoproteins, the T-cell receptor [alpha] and [beta] chains.
The CD3 antigen, which is part of the protein complex associated with the TCR (Fig.
With one specific binding site the antibody attaches to the CD3 antigen, which is present on all T cells, and with the other one it binds to a surface antigen on tumor cells.