CD26

CD26

a type II transmembrane protein present on mature T cells, some B cells, apical membranes of epithelial and endothelial cells, kidney, intestinal brush borders, and liver bile canaliculi; combines with collagen and associates with adenosine deaminase.

DPP4

A gene on chromosome 2q24.3 that encodes dipeptidyl-peptidase 4, a ubiquitous, membrane-bound enzyme with roles in nutrition, metabolism, the endocrine system, immune regulation (for instance, it is essential for T-cell receptor (TCR)-mediated T-cell activation), bone marrow mobilisation, apoptosis, cell adhesion and tumourigenesis.
References in periodicals archive ?
Known as LCA60, it binds to the virus when it encounters it, preventing the virus from binding to CD26 receptor cells.
CD3, CD4, CD9, CD11, CD19, CD20, CD22, CD26, CD27, CD28, CD29, CD33, CD37, CD40, CD44, CD45, CD47, CD52u CD55, CD56, CD66, CD70, CD74, CD80, CD95, CD98, CD100, CD117, CD135, CD137, CD152, CD200, CD223, CD227, CD246, CD248, CD274, CD276, CD279
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Peripheral blood flow cytometry confirmed a T-PLL with lymphocytes expressing CD2, CD3, CD4, CD5, CD7, CD26, and CD52.
AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis.
Circulating cytokines and soluble CD23, CD26 and CD30 in ANCAassociated vasculitides.
Each case was assessed with a variable combination of the following antibodies, specific for CD2, CD3 (surface), CD4, CD5, CD7, CD8, CD14, CD16, CD19, CD20, CD25, CD26, CD30, CD38, CD45, CD56, and monoclonal [kappa] and [lambda] (all from BD Biosciences, San Diego, Calif, except CD30, which was from Immunotech/Beckman-Coulter, Fullerton, Calif).
Fusin arrives center stage almost 3 years after a French research group announced that a molecule called CD26 was the elusive HIV fusion cofactor.
Engraftment preclinical and clinical enhancements such as use of prostaglandin E2, inhibition of cell surface protein CD26, expansion of shortterm
Of these, only residue 434 falls within the proposed receptor binding domain of spike protein, but it is located at the core (stem) subdomain of the receptor binding domain, suggesting that the camel MERS-CoV is still likely to bind human CD26 (online Technical Appendix Figure).
Thierry Dervieux(1), Diana Orentas Lein(1), Grace Park(2), John Marcelletti(1), Gary Meyer(1), Katie Smith(1), Michael Walsh(1), Joel Kremer(3), Daniel Furst(2) * Responder Phenotype and Disease Activity of Rheumatoid Arthritis (RA) Patients Receiving Methotrexate (MTX) Are Correlated with Levels of Soluble CD26 and CD30.
Engraftmentpreclinical and clinical enhancements such as use of prostaglandin E2, inhibition of cell surface protein CD26, expansion of shortterm