MRC1

(redirected from CD206)

MRC1

A gene on chromosome 10p12.33 that encodes a C-type lectin domain protein which is a type-I membrane receptor. MRC1 mediates the endocytosis of glycoproteins by macrophages by binding to high-mannose structures on the surface of viruses, bacteria and fungi, so as to facilitate engulfment by phagocytes.
References in periodicals archive ?
NADPH oxidase of human dendritic cells: role in Candida albicans killing and regulation by interferons, dectin-1 and CD206.
Exploitation Targeting Of The CD206 Receptor In Lymph Node-Resident Reticuloendothelial Cells With A Novel Synthetic 99mTc-ligand (Tilmanocept) Significantly Enhances Localization In Contrast To 99mTc-Colloid: A New Meta-analysis
Enhanced Sentinel Node Evaluation in Breast Cancer, Melanoma, and Head/Neck Squamous Cell Carcinoma Via CD206 Receptor Targeting With Tc99m-tilmanocept
Tc99m Tilmanocept, A CD206 ILM Agent, Has >24 Hour Stability in Nodes and Concordance with Imaging in Breast Cancer