KLRB1

(redirected from CD161)

KLRB1

A gene on chromosome 12p13 that encodes a C-type lectin domain protein which is expressed in natural killer (NK) cells and is involved in regulating their activity. KLRB1 inhibits NK-cell cytotoxicity and enhances anti-CD3-induced T-cell proliferation.
References in periodicals archive ?
Compared to MPB, only CD158a expression was significantly lower in APB and there wasn't a difference in the expression of CD161 and anti-Hu-KIR (p=0.
1, CCL27, CD161 and Calmodulin-dependent protein kinase when compared to WT DC.