CD16


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CD16

a type I transmembrane protein found on natural killer cells and macrophages that is involved in directing NK cell activation.
References in periodicals archive ?
CRP (50 [micro]g/mL) significantly increased EMP number, and this was significantly decreased by pretreatment with sepiapterin and DETA NONOate and antibodies to CD32 and CD64 but not CD16 (Fig.
6] The lymphoma cells express the natural killer cell marker CD56, but not the natural killer cell markers CD16 and CD57.
Another immunologic cell group, NK or CD16 cells, specialize in killing virus-infected cells and neoplastic cells by secreting cytotoxins.
Fc[gamma] receptors CD16, CD32, and CD64 have been reported as the receptors for CRP (7-9).
At the end of termination, the cell surface expression of CD16, CD69, CXCR2 and induction of apoptosis were analyzed using flow cytometry.
Analysis of the duodenal biopsy with a 4-color flow cytometer (Cytomics FC500, Beckman Coulter, Fullerton, Calif) demonstrated an abnormal T-cell population that expressed 99% CD2, 4% CD3, 100% cytoplasmic CD3, 4% CD4, 2% CD5, 99% CD7, 98% CD8, 2% CD16, 2% CD25, 98% CD56, 2% CD57, and 94% CD103 positive cells (Figure 2, A through F).
TJ-48 increased the populations of CD16 + CD158a + and CD16 + CD158b + cells in a dose-dependent manner.
Alefacept, an immunomodulatory recombinant LFA-3/IgG1 fusion protein, induces CD16 signaling and CD2/CD16-dependent apoptosis of [CD.
This portfolio includes CD138, useful for purging myeloma cells; CD25, a T cell activation marker that may facilitate the removal of alloreactive cells (thought to be responsible for GVHD) from a stem cell graft prior to transplant; CD56 and CD16, markers for NK (natural killer) cells; CD14, a monocyte marker; and CD4, the marker for T-helper cells.
Each case was assessed with a variable combination of the following antibodies, specific for CD2, CD3 (surface), CD4, CD5, CD7, CD8, CD14, CD16, CD19, CD20, CD25, CD26, CD30, CD38, CD45, CD56, and monoclonal [kappa] and [lambda] (all from BD Biosciences, San Diego, Calif, except CD30, which was from Immunotech/Beckman-Coulter, Fullerton, Calif).
The laboratory findings revealed that she had an intact adaptive immunity for varicella but lack of lymphocytes expressing CD56 or CD16 and lack of demonstrable NK cell cytotoxicity and antibody-dependent cell-mediated cytotoxicity.