According to the WHO classification (2), Hodgkin and Reed-Sternberg cells are almost always positive for CD30 and positive for CD15
in 75-85% of cases.
Conclusion: We found that a panel including calretinin and CK5/6 for malignant mesothelioma and CEA and CD15
for adenocarcinoma and additionally EMA and TTF-1 avoided the difficulty in all cases.
Immunohistochemistry: Formalin-fixed paraffin- embedded LN specimens were stained immunohistochemically with primary monoclonal antibodies against CD45, CD20, CD45RO, CD15
and CD30 antigens for immunophenotyping and classifying HL according to the WHO classification (15), bcl-2 (clone 124), p53 (clone DO7), EBV-LMP1 (clone CS 1-4), Ki-67 (clone MIB-1) and with polyclonal rabbit anti bak, as described earlier (11).
Further workup with immunohistochemical stains revealed that the lesion was CD45 positive (hematopoietic); it also stained with CD15
, CD68, and CD168 (Figure 2).
Highest expression of CD133 or CD15
occurred in a [CD24.
Seven monoclonal antibodies for a set of leukocyte surface antigens (including CD13, CD15
, CD33, CD34, HLA-DR, CD14, and CD45) have been immobilized on a modified slide (left side of Fig.
These cells were focally positive for CD3O (Ki1) and Ebstein-Barr virus latent membrane protein-1 (EBVLMP-1) and negative for CD15
This request is for a one-time purchase of two (2) Lily Corporation CD15
Epoxy Injection Dispenser for the Michigan Department of Transportation (MDOT).
High myeloid expression of CD13, CD33, and CD15
in 75% of lymphoblasts in Ph(-) ALL has been observed.
Usual B and T cell markers (CD3, CD5, CD10, CD15
, CD20, CD79a, PAX5) were negative, and activation markers (CD30 and MUM1) were positive in this tumor.
Accordingly, reactivity for the lymphoid markers Tdt, CD2, CD7, and CD19 was demonstrated in MPO+ myeloid leukemic cells (68-73, 75-80), whereas positivity for the myeloid antigens CD13, CD33, and CD15
can be found in a variable proportion of ALL cases (50, 54, 74).
Immunohistochemically, the tumor cells are positive for CD15
, CD30, Pax5, and rarely CD20, and negative for T-cell markers.