CDH5

(redirected from CD144)

CDH5

A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH5 is thought to play a key role in endothelial cell biology by controlling cohesion and organisation of intercellular junctions.
References in periodicals archive ?
We incubated 10 [micro]L EMP suspension with 10 [micro]L antihuman/rat E-selectin, CD144, CD31, and CD42 or isotype control.
Whereas we show increased positivity for CD144, CD31, and E-selectin (to phenotypically represent EMPs), we have also examined positivity of Annexin, CD51, and CD61 (markers expressed on EMPs) and obtained results similar to those seen in Fig.
Tumor cells stain for the usual vascular and endothelial markers including CD31, CD34, CD144 (VE-cadherin), and at least focally for factor VIII-related antigen.