CD11c


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CD11c

a type I transmembrane protein found on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
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The microglia express a molecule, CD11c, on their surface.
Flow cytometry showed a 96% variable size, clonal B cell population expressing CD10, CD11c, CD19, CD20, CD22, CD45, CD52, CD103, CD123, BCL2, and Kappa.
Lachesis muta increased CD3, CD45R and, CD11c expression and decreased CD11b.
These immunohistochemical studies included reagents specific for CD3, CD11c, CD20, CD33, CD43, CD68, CD117, CD163, lysozyme, and myeloperoxidase.
2 Ab (Caltag Laboratories); or ii) PE-conjugated rat anti-mouse CD86 Ab (Caltag Laboratories), biotinylated Armenian hamster anti-mouse CD11c Ab (BD Pharmingen), and FITC-conjugated rat anti-mouse CD8[alpha]Ab (Serotec Ltd.
Immunophenotyping was strongly positive for CD5, CD45, CD19, CD22, FMC-7, S-Ig and CD38, moderately positive for CD11c, weakly positive for CD23, and negative for CD-103 and ZAP 70.
E) mRNA levels of F4/80, Cd11c, Mb, Il6, Tnfa, and Ccl2 in adipose tissue evaluated by RT-PCR.
Flow cytometric analysis exhibited [lambda] monoclonal B cells with coexpression of CD10 and FMC-7, which were negative for CD5, CD23, CD11c, CD25, CD103, and [kappa] light chain.
The two distinct subsets of blood DCs, the CD11c expressing myeloid dendritic cells (mDCs), and the CD11c lacking plasmacytoid dendritic cells (pDCs) have distinct morphology and functions.
Cells that were negative for CD3 and CD16 and positive for CD11c, CD11b, and CD14 were subsequently analyzed for endoglin production.
Hairy cells will often demonstrate bright CD22 and CD11c co-expression and segregate out as a distinct population on two-color flow cytometric analysis.
Proteoglycan isolated from Phellinus linteus inhibits tumor growth through mechanisms leading to an activation of CD11c + CD8 + DC and type I helper T cell-dominant immune state, FEBS Letters 576, 391-400.