CD10

CD10

a type II transmembrane protein found on pre-B cells, germinal-center B cells, some neutrophils, kidney cells, T-cell precursors, and epithelial cells that acts as a zinc metalloprotease cleaving peptide bonds on the amino side of hydrophobic amino acids; expressed in acute lymphocytic leukemia and follicular-center-cell lymphomas.
References in periodicals archive ?
Tumour cells demonstrated immunopositivity for pancytokeratin, vimentin, CD10, CK19 and AMACR (Fig.
The tumor cells were immunohistochemically reactive for RCC antigen, CD10, CK903, P504-S (AMACR), and PAX8.
Immunohistochemical studies were undertaken using antibodies CK7 (1:750 Dako), cytokeratin AE1/AE3 (1:1000 Dako), EMA (1:750 Dako), CD10 (1:300 Novocastra), vimentin (1:4000 Dako), S100 (1:4000 Dako), TTF-1 (1:250 Novocastra) and thyroglobulin (1:500 Dako).
In general, most cases of lymphoblastic lymphoma/ leukemia involving extramedullary sites are of immature T-cell lineage, express a variety of T-cell antigens as well as CD10 and TdT (bright, often uniform), and are negative for myeloperoxidase, lysozyme, and CD68.
ECE-1 and CD10 protein expression in invasive breast cancer.
CD3 and CD10 staining were performed and showed an admixture of T cells and B cells; no evidence of malignancy was found.
In some instances, having a CD10 conviction could add as much as an extra [pounds]402 to the cost, an increase of 63 per cent.
Pathological analysis revealed a malignant spindle cell tumor with negative immunohistochemical staining for CD117 and CD10 and mild reactivity for desmin and muscle specific actin, making low grade leiomyosarcoma the most likely diagnosis.
The majority of children will develop common ALL, which characteristically has CD10 expression on the surface of the leukaemia blasts.
Biyopsi materyalinin immunohistokimyasal incelemesinde CD-20 pozitifligi, CD3, CD5, CD10 negatifligi saptandi.