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CCR-5

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CCR-5
CMKBR2, CC CKR2, ChemR13 Cell biology A 40 kD receptor encoded on chromosome 3q21; CCR-5 is a coreceptor for SIV and HIV which, with CD4, provides the portal for HIV entry into macrophages Ligands MIP-1a, MIP-1b, RANTES. See AIDS, Coreceptor, HIV.

CCR-5
AIDS, Molecular medicine The gene that encodes CCR-5 which, when mutated, encodes a defective receptor protein incapable of being infected with HIV. See AIDS, CXCR4, HIV.


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