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CCR-1

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CCR-1
RANTES–Regulated upon Activation Normal T-cell Expressed & Secreted AIDS, Molecular medicine A chemokine for CCR-5 receptor which blocks the entry of M-tropic strains of HIV, which preferentially infect macrophages; it is secreted by CD8 T cells, platelets, renal epithelial, and mesangial cells, and is chemoattractive for basophils, eosinophils, monocytes, and T cells; it activates basophils, inducing histamine release. See AIDS, CCR-3, CCR-5, Chemokine, HIV.


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