CCNT1

CCNT1

A gene on chromosome 12q13.11 that encodes a member of the highly conserved cyclin family, which regulates CDK kinases. Cyclin T1 binds tightly to CDK9, forming a major subunit of the transcription elongation factor p-TEFb, which interacts with, and acts as a cofactor of, HIV-1’s Tat protein, and is required for full activation of viral transcription.
References in periodicals archive ?
Total Tag SNPs Gene inclusion tag passing Gene SNPs inclusion criteria criteria AHRR 27 24 AIP/ARA9/XAP2 2 0 ARNT 5 4 Canonical AhR AhR 11 8 HSP90 6 4 p23/TGES3 4 4 ARNTL 19 14 CCNT1 3 3 DAP3 3 1 ESR1/ER-a 49 33 GTF2F1 3 1 GTF2F2 9 6 HIF1A/MOP1 6 2 NCOA1/SRC1/RIP160 11 6 NCOA2/SRC2 19 14 NEDD8 4 4 NR2F1 2 2 AhR interacting genes (Entrez Gene) NRIP1/RIP140 10 8 RB1 4 4 RELA/NFKB3 4 2 SMARCA4 10 6 SP1 4 4 SRC 14 10 TAF4 6 4 TAF6 6 4 TBP 6 3 XPO1 5 5 AR 2 0 CREB1 4 3 ERB/ESR2 16 12 GR/NR3C1 18 15 GSTCD 5 5 AhR interacting genes (STRING) GSTM1 1 0 MYC 6 5 PPARA 16 11 RELB 6 4 UGT1A5 16 10 CYP1A1 2 1 CYP1A2 2 1 Dioxin-induced genes CYP1B1 6 5 TP53 5 1 ARNT2 58 36 Genes associated with reproductive CYP17A1 6 4 outcomes: Sone and Yonemoto 2008 9q31.