CCNB2

CCNB2

A gene on chromosome 15q22.2 that encodes cyclin B2, which is essential for controlling the cell cycle at the G2/M transition. Cyclin B2 interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex, the maturation promoting factor.
References in periodicals archive ?
HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas.
Other upregulated genes were related to cell proliferation and its control, such as cyclin-dependent kinase gene CDK1/CDC2; cyclin genes CCNA2, CCNB1, CCNB2, and CCNL2; the DLG7 component of the mitotic apparatus; the gene encoding the checkpoint kinase involved in response to DNA damage, CHEK1/CHK1; and BUB1 and MAD2L1, components of the spindle checkpoint.