CCL18


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CCL18

A gene on chromosome 17q11.2 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL18 is chemotactic for naïve T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. It attracts naïve T cells toward dendritic cells and activated macrophages in lymph nodes, and may play a role in humoral and cell-mediated immune responses.
References in periodicals archive ?
A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18.
References Marker LSD Immune quantification (protein) Protein [alpha]-L-Iduronidase MPS I 37 Iduronate-2-sulfatase MPS II 42, 61, 74 Sulfamidase MPS IIIA 39 N-Acetyl-galactosamine- MPS VI 38, 43, 72, 73 4-sulfatase [alpha]-Galactosidase Fabry 41 Saposin C Fabry 41 Saposin C Multiple 69, 70 Acid [alpha]-glucosidase Pompe 40 [beta]-Glucosidase Gaucher 44 LAMP-1 Multiple 68, 70 LAMP-2 Multiple 78 CCL18 Gaucher 79 Chitotriosidase (a) Gaucher Substrate [G.