TRPV6

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TRPV6

A gene on chromosome 7q34 that encodes a calcium-permeable channel, which participates in neurotransmission, muscle contraction and exocytosis by providing calcium as an intracellular second messenger; transcellular calcium transport may be regulated by vitamin D, parathyroid hormone or calcitonin. The TRPV6 channel is activated by a low internal calcium levels, and involved in Ca2+ absorption and reabsorption in the kidney and intestine.
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