VLDLR

(redirected from CARMQ1)

VLDLR

A gene on chromosome 9p24 that encodes a cell surface protein  involved in receptor-mediated endocytosis of very low-density lipoprotein (VLDL), and transports it into cells by endocytosis. Internalisation of the receptor-ligand complex requires clustering into clathrin-coated pits.

Molecular pathology
VLDLR mutations cause VLDLR-associated cerebellar hypoplasia.