CARD14

CARD14

A gene on chromosome 17q25 that encodes a protein which activates NF-kappa-B via BCL10 and IKK and stimulates the phosphorylation of BCL10. CARD 14 is expressed in the placenta.
References in periodicals archive ?
sup][1] Recent studies have discovered several susceptibility genes for psoriasis, some of which, such as interleukin 36 receptor antagonist ( IL36RN ) and caspase recruitment domain family member 14 ( CARD14 ), are shared between PP and PsV.
For instance, mutations of IL36RN , CARD14 , and AP1S3 genes are associated with GPP.
Variant analysis of CARD14 in a Chinese Han population with psoriasis vulgaris and generalized pustular psoriasis.