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CAPRIE |
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CAPRIE Cardiology A clinical trial–Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events which compared the efficacy of the antiplatelet agent, clopidogrel, with aspirin therapy as a stroke prophylaxis. See Clopidogrel. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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However, Prasugrel has to go through an intensive Phase III clinical program to translate the better platelet inhibition seen in Phase I studies to improved clinical outcomes in terms of reducing MI and other CAD instances and death compared to Clopidogrel - essentially an expensive and time consuming study similar to CAPRIE study done for establishing Clopidogrel's marginal superiority over Aspirin. The CAPRIE (1996) study showed that PLAVIX(R) (Clopidogrel) and Aspirin are quite toxic with over 50% of those who take either of them suffer from various toxic side effects. The CAPRIE (1996) study showed that the largest selling antiplatelet drugs PLAVIX(R) (Clopidogrel) and Aspirin are quite toxic with over 50% of those who take either of them suffer from various toxic side effects. |
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