IFIH1

(redirected from CADM-140 autoantigen)

IFIH1

A gene on chromosome 2q24.2 that encodes an RNA helicase which, through its ATP-dependent unwinding of RNA, may promote message degradation by specific RNases. It is thought to have roles in suppressing growth and involved in innate immune defence viruses.

Molecular pathology
Genetic variation in IFIH1 is associated with diabetes mellitus insulin-dependent type 19.